454 is an edible-grade essential oil technology built to support vascular function, heat resilience, dry matter intake, and performance consistency in cattle under stress.
Helps cattle stay cooler and keep eating through summer heat stress.
Supports dry matter intake when heat would normally reduce consumption.
Helps reduce heat-related setbacks during severe summer weather events.
Real-world cattle data shows how 454 supports intake, performance, and heat resilience when conditions work against the herd.
Average daily gain range reported in summer feedlot trial cattle fed 454.
Dry matter intake exceeded 2.75% of body weight in pens fed 454.
Listed cost at 350 mg per head per day.
More than 1 million feedlot cattle consumed 454 during summer months in 2017.
Meet 454
454 is a precision blend of edible-grade essential oils developed to improve vascular function, stabilize intake, and enhance metabolic efficiency in cattle.
Originally developed to address fescue-related vasoconstriction, 454 is now widely used in feedlot and dairy systems for:
Field data shows cattle on 454 maintain intake and performance even under extreme heat conditions, with ADG reaching 4.5–5.0 lbs/day in summer trials.
During severe heat events, operations using 454 saw near-zero mortality compared to significant losses in control yards
454 is an edible-grade essential oil technology selected for vasodilation, antioxidant, and nutraceutical properties — built to support cattle through heat, intake, and vascular stress.
454 was developed from research around fescue-related vascular stress and heat intolerance. The goal is to help cattle maintain intake, comfort, and performance when environmental or vascular pressure increases.
Feedlot cattle fed 454 maintained dry matter intake above 2.75% of body weight.
Summer trial cattle fed 454 reported average daily gains in the 4.5–5.0 lb range.
Dairy records reported first-service conception-rate improvements in Southwest and Midwest herds.
454 Profitability
When blood flow is restricted (heat stress, ergovaline exposure), cattle:
454 supports:
Up to 35% improvement in conception rates in dairy systems
~1.4°F reduction in body temperature in breeding trials
Maintained intake during 120°F heat events with no production drop.
A simple mechanism-to-outcome visual for homepage use, sales decks, or partner pages. Designed to show the biological problem, the functional role of 454, and the measurable production outcomes that matter to nutritionists and feedlots.
Heat stress and ergovaline exposure contribute to vasoconstriction.
Restricted blood flow can reduce intake, gain, and reproductive efficiency.
454 supports vasodilation and helps cattle stay more resilient under stress.
Improved heat tolerance and more stable physiological performance.
More consistent feed intake and less performance disruption during heat events.
Better growth consistency, stronger breeding performance, and more reliable outcomes.
454 is built for cattle programs facing heat, intake pressure, vascular stress, or performance disruption.
454 supports feedlot programs focused on heat abatement, consistent dry matter intake, average daily gain, feed efficiency, and fewer cattle in sick pens.
Practical feeding rates make 454 easy to position in seasonal, receiving, and finishing programs.
per head per day for 21 days
per head per day from May through September
Feeding rates should be reviewed with your nutritionist based on cattle class, heat risk, season, and program goals.
During a severe Kansas heat event with high heat, humidity, and little wind, some feedyards reportedly lost up to 500 head on the worst days.
Several yards were placed on 454 at 1,000 mg per head per day, and by Monday most cattle were back at the bunk with mortalities dropping to almost nothing.
Supports heat abatement, consistent dry matter intake, average daily gain, feed efficiency, and fewer cattle in sick pens.
Supports breeding, consistent feed intake, production, and overall herd health. Dairy records reported first-service conception-rate improvements after feeding 454.
Meet AP5
In AP-5, 454 works alongside binders and enzymatic support to help address the vascular effects of ergovaline exposure.
AP-5 combines:
This creates a multi-pathway solution to fescue toxicosis:
AP-5 demonstrates how 454 can be formulated into a differentiated, high-value product category.
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